Metabolomic Analysis of Exercise Effects in the POLG Mitochondrial DNA Mutator Mouse Brain

Mitochondrial DNA (mtDNA) mutator mice express a mutated form of mtDNA polymerase gamma (PolgA) that results an accelerated accumulation of somatic mtDNA mutations in association with a premature aging phenotype. An exploratory metabolomic analysis of cortical metabolites in sedentary and exercised...

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Publicado en:Neurobiol Aging
Autores principales: Clark-Matott, Joanne, Saleem, Ayesha, Dai, Ying, Shurubor, Yevgeniya, Ma, Xiaoxing, Safdar, Adeel, Beal, M. Flint, Tarnopolsky, Mark, Simon, David K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609600/
https://ncbi.nlm.nih.gov/pubmed/26294258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.07.020
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