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Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington’s disease

Huntington’s disease (HD) is a devastating illness and at present there is no disease modifying therapy or cure for it; and management of the disease is limited to a few treatment options for amelioration of symptoms. Recently, we showed that the administration of bezafibrate, a pan-PPAR agonist, in...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Chandra, Abhishek, Sharma, Abhijeet, Calingasan, Noel Y., White, Joshua M., Shurubor, Yevgeniya, Yang, X. William, Beal, M. Flint, Johri, Ashu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081058/
https://ncbi.nlm.nih.gov/pubmed/27008868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw095
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