Caricamento...

Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca(2+)

The mechanism underlying the inflammatory role of TRPA1 in lung epithelial cells (LECs) remains unclear. Here, we show that cigarette smoke extract (CSE) sequentially induced several events in LECs. The Ca(2+) influx was prevented by decreasing extracellular reactive oxygen species (ROS) with the sc...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mediators Inflamm
Autori principali: Lin, An-Hsuan, Liu, Meng-Han, Ko, Hsin-Kuo, Perng, Diahn-Warng, Lee, Tzong-Shyuan, Kou, Yu Ru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609484/
https://ncbi.nlm.nih.gov/pubmed/26504357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/148367
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !