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Formation and Maturation of Phase Separated Liquid Droplets by RNA Binding Proteins

Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA binding proteins containing disordered regions. We demonstrate that the disordered regions of key RNP granule components, and the full-length granule protein hnRNPA1, can phase separate in vitro...

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Bibliografske podrobnosti
izdano v:Mol Cell
Main Authors: Lin, Yuan, Protter, David S. W., Rosen, Michael K., Parker, Roy
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609299/
https://ncbi.nlm.nih.gov/pubmed/26412307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.08.018
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