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Formation and Maturation of Phase Separated Liquid Droplets by RNA Binding Proteins
Eukaryotic cells possess numerous dynamic membrane-less organelles, RNP granules, enriched in RNA and RNA binding proteins containing disordered regions. We demonstrate that the disordered regions of key RNP granule components, and the full-length granule protein hnRNPA1, can phase separate in vitro...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609299/ https://ncbi.nlm.nih.gov/pubmed/26412307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.08.018 |
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