Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma

PURPOSE: The current study presents [(18)F]PARPi-FL as a bimodal fluorescent/positron emission tomography (PET) agent for PARP1 imaging. PROCEDURES: [(18)F]PARPi-FL was obtained by (19)F/(18)F isotopic exchange and PET experiments, biodistribution studies, surface fluorescence imaging, and autoradio...

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Publicat a:Mol Imaging Biol
Autors principals: Carlucci, Giuseppe, Carney, Brandon, Brand, Christian, Kossatz, Susanne, Irwin, Christopher P., Carlin, Sean D., Keliher, Edmund J., Weber, Wolfgang, Reiner, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609241/
https://ncbi.nlm.nih.gov/pubmed/25895168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-015-0858-0
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