Lenalidomide Enhances Immune Checkpoint Blockade Induced Immune Response in Multiple Myeloma

PURPOSE: PD1/PD-L1 signaling promotes tumor growth while inhibiting effector cell-mediated anti-tumor immune responses. Here we assessed the impact of single and dual blockade of PD1/PD-L1, alone or in combination with lenalidomide, on accessory and immune cell function as well as multiple myeloma (...

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Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Görgün, Güllü Topal, Samur, Mehmet K., Cowens, Kristen B., Paula, Steven, Bianchi, Giada, Anderson, Julie E., White, Randie E., Singh, Ahaana, Ohguchi, Hiroto, Suzuki, Rikio, Kikuchi, Shohei, Harada, Takeshi, Hideshima, Teru, Tai, Yu-Tzu, Laubach, Jacob P., Raje, Noopur, Magrangeas, Florence, Minvielle, Stephane, Avet-Loiseau, Herve, Munshi, Nikhil C., Dorfman, David M., Richardson, Paul G., Anderson, Kenneth C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609232/
https://ncbi.nlm.nih.gov/pubmed/25979485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0200
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