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Pioglitazone Attenuates Acute Cocaine Toxicity in Rat Isolated Heart: Potential Protection by Metabolic Modulation
BACKGROUND: The authors test whether cocaine depresses mitochondrial acylcarnitine exchange and if a drug that enhances glucose metabolism could protect against cocaine-induced cardiac dysfunction. METHODS: Oxygen consumption with and without cocaine was compared in rat cardiac mitochondria using ei...
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Publicado no: | Anesthesiology |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609210/ https://ncbi.nlm.nih.gov/pubmed/21487283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318218a7f6 |
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