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Caffeine, through adenosine A(3) receptor-mediated actions, suppresses amyloid beta precursor protein internalization and amyloid beta generation
Intraneuronal accumulation and extracellular deposition of amyloid beta (Aβ) protein continues to be implicated in the pathogenesis of Alzheimer’s disease (AD), be it familial in origin or sporadic in nature. Aβ is generated intracellularly following endocytosis of amyloid beta precursor protein (Aβ...
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| Publicado en: | J Alzheimers Dis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609209/ https://ncbi.nlm.nih.gov/pubmed/26402756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-142223 |
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