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Caffeine, through adenosine A(3) receptor-mediated actions, suppresses amyloid beta precursor protein internalization and amyloid beta generation
Intraneuronal accumulation and extracellular deposition of amyloid beta (Aβ) protein continues to be implicated in the pathogenesis of Alzheimer’s disease (AD), be it familial in origin or sporadic in nature. Aβ is generated intracellularly following endocytosis of amyloid beta precursor protein (Aβ...
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| Veröffentlicht in: | J Alzheimers Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609209/ https://ncbi.nlm.nih.gov/pubmed/26402756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-142223 |
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