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e-Driver: a novel method to identify protein regions driving cancer

Motivation: Most approaches used to identify cancer driver genes focus, true to their name, on entire genes and assume that a gene, treated as one entity, has a specific role in cancer. This approach may be correct to describe effects of gene loss or changes in gene expression; however, mutations ma...

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Vydáno v:Bioinformatics
Hlavní autoři: Porta-Pardo, Eduard, Godzik, Adam
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609017/
https://ncbi.nlm.nih.gov/pubmed/25064568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu499
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