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Intracellular sphingosine kinase 2–derived sphingosine-1-phosphate mediates epidermal growth factor–induced ezrin-radixin-moesin phosphorylation and cancer cell invasion
The bioactive sphingolipid sphingosine-1-phosphate (S1P) mediates cellular proliferation, mitogenesis, inflammation, and angiogenesis. These biologies are mediated through S1P binding to specific GPCRs [sphingosine-1-phosphate receptor (S1PR)1–5] and some other less well-characterized intracellular...
שמור ב:
| הוצא לאור ב: | FASEB J |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Federation of American Societies for Experimental Biology
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608912/ https://ncbi.nlm.nih.gov/pubmed/26209696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-274340 |
| תגים: |
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