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Arrhythmogenic Remodeling of β(2) versus β(1) Adrenergic Signaling in the Human Failing Heart

BACKGROUND: Arrhythmia is the major cause of death in patients with heart failure, for which β-adrenergic receptor (AR) blockers are a mainstay therapy. But the role of β-adrenergic signaling in electrophysiology and arrhythmias has never been studied in human ventricles. METHODS AND RESULTS: We use...

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Detalhes bibliográficos
Publicado no:Circ Arrhythm Electrophysiol
Main Authors: Lang, Di, Holzem, Katherine, Kang, Chaoyi, Xiao, Mengqian, Hwang, Hye Jin, Ewald, Gregory A., Yamada, Kathryn A., Efimov, Igor R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608687/
https://ncbi.nlm.nih.gov/pubmed/25673629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.114.002065
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