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Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System

Fluoroform (HCF(3), HFC-23) is a side product in the manufacture of polytetrafluoroethylene (Teflon). Despite its attractive properties, taming HCF(3) for trifluoromethylation is quite problematic owing to its low acidity and the lability of the naked trifluoromethyl carbanion generated from HCF(3)....

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Publicado en:ChemistryOpen
Main Authors: Okusu, Satoshi, Hirano, Kazuki, Tokunaga, Etsuko, Shibata, Norio
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608523/
https://ncbi.nlm.nih.gov/pubmed/26491635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201500160
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