RNA-seq Reveals Aurora Kinase Driven-mTOR Pathway Activation in Patients with Sarcomatoid Metastatic Renal Cell Carcinoma

Sarcomatoid metastatic renal cell carcinoma (mRCC) is associated with a poor prognosis and the biology of the disease has been inadequately characterized. RNA sequencing (RNA-seq) was performed on adjacent benign, clear cell, and sarcomatoid components from clinical specimens with sarcomatoid mRCC....

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Gepubliceerd in:Mol Cancer Res
Hoofdauteurs: Pal, Sumanta K., He, Miaoling, Tong, Tommy, Wu, Huiqing, Liu, Xueli, Lau, Clayton, Wang, Jin-Hui, Warden, Charles, Wu, Xiwei, Signoretti, Sabina, Choueiri, Toni K., Karam, Jose A., Jones, Jeremy O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608366/
https://ncbi.nlm.nih.gov/pubmed/25183163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0352
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