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Using water–solvent systems to estimate in vivo blood–tissue partition coefficients

BACKGROUND: Blood–tissue partition coefficients indicate how a chemical will distribute throughout the body and are an important part of any pharmacokinetic study. They can be used to assess potential toxicological effects from exposure to chemicals and the efficacy of potential novel drugs designed...

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Publicado en:Chem Cent J
Autores principales: Derricott, Caitlin E., Knight, Emily A., Acree, William E., Lang, Andrew SID
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608262/
https://ncbi.nlm.nih.gov/pubmed/26478743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-015-0134-z
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