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Using water–solvent systems to estimate in vivo blood–tissue partition coefficients
BACKGROUND: Blood–tissue partition coefficients indicate how a chemical will distribute throughout the body and are an important part of any pharmacokinetic study. They can be used to assess potential toxicological effects from exposure to chemicals and the efficacy of potential novel drugs designed...
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| Veröffentlicht in: | Chem Cent J |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608262/ https://ncbi.nlm.nih.gov/pubmed/26478743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-015-0134-z |
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