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Using water–solvent systems to estimate in vivo blood–tissue partition coefficients

BACKGROUND: Blood–tissue partition coefficients indicate how a chemical will distribute throughout the body and are an important part of any pharmacokinetic study. They can be used to assess potential toxicological effects from exposure to chemicals and the efficacy of potential novel drugs designed...

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Detalhes bibliográficos
Publicado no:Chem Cent J
Main Authors: Derricott, Caitlin E., Knight, Emily A., Acree, William E., Lang, Andrew SID
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608262/
https://ncbi.nlm.nih.gov/pubmed/26478743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-015-0134-z
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