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Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

Factor XIII(a) [FXIII(a)] stabilizes clots and increases resistance to fibrinolysis and mechanical disruption. FXIIIa also mediates red blood cell (RBC) retention in contracting clots and determines venous thrombus size, suggesting FXIII(a) is a potential target for reducing thrombosis. However, the...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Byrnes, James R., Duval, Cédric, Wang, Yiming, Hansen, Caroline E., Ahn, Byungwook, Mooberry, Micah J., Clark, Martha A., Johnsen, Jill M., Lord, Susan T., Lam, Wilbur A., Meijers, Joost C. M., Ni, Heyu, Ariëns, Robert A. S., Wolberg, Alisa S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608241/
https://ncbi.nlm.nih.gov/pubmed/26324704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-652263
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