Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

BACKGROUND: Obesity, defined as pathologically increased body mass index (BMI), is strongly related to an increased risk for numerous common cardiovascular and metabolic diseases. It is particularly associated with insulin resistance, hyperglycemia, and systemic oxidative stress and represents the m...

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Bibliografiska uppgifter
I publikationen:BMC Med Genomics
Huvudupphovsmän: Homuth, Georg, Wahl, Simone, Müller, Christian, Schurmann, Claudia, Mäder, Ulrike, Blankenberg, Stefan, Carstensen, Maren, Dörr, Marcus, Endlich, Karlhans, Englbrecht, Christian, Felix, Stephan B., Gieger, Christian, Grallert, Harald, Herder, Christian, Illig, Thomas, Kruppa, Jochen, Marzi, Carola S., Mayerle, Julia, Meitinger, Thomas, Metspalu, Andres, Nauck, Matthias, Peters, Annette, Rathmann, Wolfgang, Reinmaa, Eva, Rettig, Rainer, Roden, Michael, Schillert, Arne, Schramm, Katharina, Steil, Leif, Strauch, Konstantin, Teumer, Alexander, Völzke, Henry, Wallaschofski, Henri, Wild, Philipp S., Ziegler, Andreas, Völker, Uwe, Prokisch, Holger, Zeller, Tanja
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608219/
https://ncbi.nlm.nih.gov/pubmed/26470795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0141-x
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