Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

BACKGROUND: Obesity, defined as pathologically increased body mass index (BMI), is strongly related to an increased risk for numerous common cardiovascular and metabolic diseases. It is particularly associated with insulin resistance, hyperglycemia, and systemic oxidative stress and represents the m...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Homuth, Georg, Wahl, Simone, Müller, Christian, Schurmann, Claudia, Mäder, Ulrike, Blankenberg, Stefan, Carstensen, Maren, Dörr, Marcus, Endlich, Karlhans, Englbrecht, Christian, Felix, Stephan B., Gieger, Christian, Grallert, Harald, Herder, Christian, Illig, Thomas, Kruppa, Jochen, Marzi, Carola S., Mayerle, Julia, Meitinger, Thomas, Metspalu, Andres, Nauck, Matthias, Peters, Annette, Rathmann, Wolfgang, Reinmaa, Eva, Rettig, Rainer, Roden, Michael, Schillert, Arne, Schramm, Katharina, Steil, Leif, Strauch, Konstantin, Teumer, Alexander, Völzke, Henry, Wallaschofski, Henri, Wild, Philipp S., Ziegler, Andreas, Völker, Uwe, Prokisch, Holger, Zeller, Tanja
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608219/
https://ncbi.nlm.nih.gov/pubmed/26470795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0141-x
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