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Mapping the Genetic Architecture of Gene Regulation in Whole Blood

BACKGROUND: We aimed to assess whether whole blood expression quantitative trait loci (eQTLs) with effects in cis and trans are robust and can be used to identify regulatory pathways affecting disease susceptibility. MATERIALS AND METHODS: We performed whole-genome eQTL analyses in 890 participants...

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Detalhes bibliográficos
Main Authors: Schramm, Katharina, Marzi, Carola, Schurmann, Claudia, Carstensen, Maren, Reinmaa, Eva, Biffar, Reiner, Eckstein, Gertrud, Gieger, Christian, Grabe, Hans-Jörgen, Homuth, Georg, Kastenmüller, Gabriele, Mägi, Reedik, Metspalu, Andres, Mihailov, Evelin, Peters, Annette, Petersmann, Astrid, Roden, Michael, Strauch, Konstantin, Suhre, Karsten, Teumer, Alexander, Völker, Uwe, Völzke, Henry, Wang-Sattler, Rui, Waldenberger, Melanie, Meitinger, Thomas, Illig, Thomas, Herder, Christian, Grallert, Harald, Prokisch, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989189/
https://ncbi.nlm.nih.gov/pubmed/24740359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093844
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