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Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER
BACKGROUND: Estrogen (17β-estradiol) promotes the survival and proliferation of breast cancer cells and its receptors represent important therapeutic targets. The cellular actions of estrogen are mediated by the nuclear estrogen receptors ERα and ERβ as well as the 7-transmembrane spanning G protein...
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| Veröffentlicht in: | BMC Cancer |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608161/ https://ncbi.nlm.nih.gov/pubmed/26470790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1699-6 |
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