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Targeting the Urokinase Plasminogen Activator Receptor With a Monoclonal Antibody Impairs the Growth of Human Colorectal Cancer in the Liver

BACKGROUND: Urokinase plasminogen activator receptor (uPAR) expression has been shown to correlate with poor prognosis in colorectal cancer (CRC). The authors hypothesized that targeting uPAR, a receptor involved in cell proliferation, migration, invasion, adhesion, and angiogenesis, would impair th...

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Bibliografski detalji
Izdano u:Cancer
Glavni autori: Van Buren, George, Gray, Michael J., Dallas, Nikolaos A., Xia, Ling, Lim, Sherry J., Fan, Fan, Mazar, Andrew P., Ellis, Lee M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608018/
https://ncbi.nlm.nih.gov/pubmed/19484792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24371
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