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Targeting the Urokinase Plasminogen Activator Receptor With a Monoclonal Antibody Impairs the Growth of Human Colorectal Cancer in the Liver
BACKGROUND: Urokinase plasminogen activator receptor (uPAR) expression has been shown to correlate with poor prognosis in colorectal cancer (CRC). The authors hypothesized that targeting uPAR, a receptor involved in cell proliferation, migration, invasion, adhesion, and angiogenesis, would impair th...
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Izdano u: | Cancer |
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Glavni autori: | , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2009
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608018/ https://ncbi.nlm.nih.gov/pubmed/19484792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24371 |
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