Chemoresistant Colorectal Cancer Cells, the Cancer Stem Cell Phenotype and Increased Sensitivity to Insulin-like Growth Factor Receptor-1 Inhibition

5-fluorouracil (5FU) and oxaliplatin are standard therapy for metastatic colorectal cancer (CRC), but the development of chemoresistance is inevitable. Since cancer stem cells (CSCs) are hypothesized to be chemoresistant, we investigated CSC properties in newly developed chemoresistant CRC cell line...

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Détails bibliographiques
Auteurs principaux: Dallas, Nikolaos A., Xia, Ling, Fan, Fan, Gray, Michael J., Gaur, Puja, van Buren, George, Samuel, Shaija, Kim, Michael P., Lim, Sherry J., Ellis, Lee M.
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198868/
https://ncbi.nlm.nih.gov/pubmed/19244128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2023
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