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Targeting alpha-synuclein oligomers by protein-fragment complementation for drug discovery in synucleinopathies
OBJECTIVE: Reducing the burden of alpha-synuclein oligomeric species represents a promising approach for disease-modifying therapies against synucleinopathies such as Parkinson's disease and dementia with Lewy bodies. However, the lack of efficient drug discovery strategies that specifically ta...
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| Опубликовано в: : | Expert Opin Ther Targets |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4608017/ https://ncbi.nlm.nih.gov/pubmed/25785645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2015.1009448 |
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