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Impacts of tissue-type plasminogen activator (tPA) on neuronal survival

Tissue-type plasminogen activator (tPA) a serine protease is constituted of five functional domains through which it interacts with different substrates, binding proteins, and receptors. In the last years, great interest has been given to the clinical relevance of targeting tPA in different diseases...

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Détails bibliographiques
Publié dans:Front Cell Neurosci
Auteurs principaux: Chevilley, Arnaud, Lesept, Flavie, Lenoir, Sophie, Ali, Carine, Parcq, Jérôme, Vivien, Denis
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607783/
https://ncbi.nlm.nih.gov/pubmed/26528141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00415
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