Tissue-type Plasminogen Activator (tPA) Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate

Tissue-type plasminogen activator (tPA) is a serine proteinase released by the presynaptic terminal of cerebral cortical neurons following membrane depolarization (Echeverry et al., 2010). Recent studies indicate that the release of tPA triggers the synaptic vesicle cycle and promotes the exocytosis...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Jeanneret, Valerie, Wu, Fang, Merino, Paola, Torre, Enrique, Diaz, Ariel, Cheng, Lihong, Yepes, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101231/
https://ncbi.nlm.nih.gov/pubmed/27881952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00121
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