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Tissue-type plasminogen activator regulates p35-mediated Cdk5 activation in the postsynaptic terminal

Neuronal depolarization induces the synaptic release of tissue-type plasminogen activator (tPA). Cyclin-dependent kinase-5 (Cdk5) is a member of the family of cyclin-dependent kinases that regulates cell migration and synaptic function in postmitotic neurons. Cdk5 is activated by its binding to p35...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Diaz, Ariel, Jeanneret, Valerie, Merino, Paola, McCann, Patrick, Yepes, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432712/
https://ncbi.nlm.nih.gov/pubmed/30709918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.224196
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