Second Generation 2-Aminoimidazole Based Advanced Glycation End Product Inhibitors and Breakers

The formation of advanced glycation end-products (AGE) as a result of the action of reducing sugars on host macromolecules plays a role in increased morbidity of diabetic patients. There are currently no clinically available therapeutics for the prevention or eradication of AGEs. Following our previ...

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Bibliografiska uppgifter
I publikationen:Bioorg Med Chem Lett
Huvudupphovsmän: Furlani, Robert E., Richardson, Mike A., Podell, Brendan K., Ackart, David F., Haugen, Jessica D., Melander, Roberta J., Basaraba, Randall J., Melande, Christian
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607637/
https://ncbi.nlm.nih.gov/pubmed/26187705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.06.080
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