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2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain

There is an urgent need to develop new drugs against tuberculosis. In particular, it is critical to target drug tolerant Mycobacterium tuberculosis (M. tuberculosis), responsible, in part, for the lengthy antibiotic regimen required for treatment. We previously postulated that the presence of in viv...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Jeon, Albert Byungyun, Ackart, David F., Li, Wei, Jackson, Mary, Melander, Roberta J., Melander, Christian, Abramovitch, Robert B., Chicco, Adam J., Basaraba, Randall J., Obregón-Henao, Andrés
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365497/
https://ncbi.nlm.nih.gov/pubmed/30728417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38064-7
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