The Kynurenine Pathway of Tryptophan Catabolism and AIDS-associated Kaposi's Sarcoma in Africa

BACKGROUND: Other than Kaposi's sarcoma (KS)-associated herpesvirus and CD4+ T cell lymphopenia, the mechanisms responsible for KS in the context of HIV are poorly understood. One recently explored pathway of HIV pathogenesis involves induction of the enzyme indoleamine 2,3 dioxygenase-1 (IDO),...

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Veröffentlicht in:J Acquir Immune Defic Syndr
Hauptverfasser: Byakwaga, Helen, Hunt, Peter W., Laker-Oketta, Miriam, Glidden, David V., Huang, Yong, Bwana, Bosco M, Mocello, A. Rain, Bennett, John, Walusansa, Victoria, Dollard, Sheila C., Bangsberg, David R., Mbidde, Edward K., Martin, Jeffrey N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607630/
https://ncbi.nlm.nih.gov/pubmed/26181812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000747
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