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Host Genetic Predictors of the Kynurenine Pathway of Tryptophan Catabolism Among Treated HIV-Infected Ugandans
OBJECTIVE: Plasma kynurenine/tryptophan (KT) ratio, a biomarker of indoleamine 2,3-dioxygenase-1 (IDO) activity, is a strong independent predictor of mortality in HIV-infected Ugandans initiating antiretroviral therapy (ART) and may play a key role in HIV pathogenesis. We performed a genome-wide stu...
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| Publicado no: | AIDS |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925250/ https://ncbi.nlm.nih.gov/pubmed/27088321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001124 |
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