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Structure-activity Relationship Studies of QS11, a Small Molecule Wnt Synergistic Agonist
Both the Wnt/β-catenin signaling pathway and small GTPases of the ADP-ribosylation factors (ARF) family play important roles in regulating cell development, homeostasis and fate. The previous report of QS11, a small molecule Wnt synergist that binds to ARF GTPase-activating protein 1 (ARFGAP1), sugg...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607626/ https://ncbi.nlm.nih.gov/pubmed/26152429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.06.062 |
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