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Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors

Serum amyloid A (SAA) proteins are known to be surrogate markers of sepsis, but their pathogenic roles remain poorly elucidated. Here we provide evidence to support a possible role of SAA as a pathogenic mediator of lethal sepsis. In a subset of septic patients for which serum high mobility group bo...

詳細記述

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書誌詳細
出版年:Mol Med
主要な著者: Li, Wei, Zhu, Shu, Li, Jianhua, D’Amore, Jason, D’Angelo, John, Yang, Huan, Wang, Ping, Tracey, Kevin J, Wang, Haichao
フォーマット: Artigo
言語:Inglês
出版事項: ScholarOne 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607615/
https://ncbi.nlm.nih.gov/pubmed/26052716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00109
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