Inducible T-cell receptor expression in precursor T-cells for leukemia control

Co-transplantation of hematopoietic stem cells with those engineered to express leukemia-reactive T cell receptors (TCRs) and differentiated ex vivo into precursor T cells (preTs) may reduce the risk of leukemia relapse. Since expression of potentially self-(leukemia-) reactive TCRs will lead to neg...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Hoseini, Shahabuddin S, Hapke, Martin, Herbst, Jessica, Wedekind, Dirk, Baumann, Rolf, Heinz, Niels, Schiedlmeier, Bernhard, Vignali, Dario AA, van den Brink, Marcel R.M., Schambach, Axel, Blazar, Bruce R., Sauer, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607259/
https://ncbi.nlm.nih.gov/pubmed/25652739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.20
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