Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson Disease

BACKGROUND: Parkinson disease (PD) is a progressive neurodegenerative disorder characterized by loss of dopamine neurons in the substantia nigra pars compacta (SNpc) and widespread aggregates of the protein alpha-synuclein (α-syn). Increasing evidence points to inflammation as a chief mediator; howe...

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Udgivet i:PLoS One
Main Authors: Thome, Aaron D., Standaert, David G., Harms, Ashley S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607155/
https://ncbi.nlm.nih.gov/pubmed/26469270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140566
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