Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterized by intracellular alpha-synuclein (α-syn) inclusions, progressive death of dopaminergic neurons in the substantia nigra pars compacta (SNpc), and activation of the innate and adaptive immune systems. Disruption of immune signaling between the cent...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Neuroinflammation
Glavni autori: Williams, Gregory P., Schonhoff, Aubrey M., Jurkuvenaite, Asta, Thome, Aaron D., Standaert, David G., Harms, Ashley S.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117927/
https://ncbi.nlm.nih.gov/pubmed/30165873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1286-2
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items