ZIC2-dependent OCT4 activation drives self-renewal of human liver cancer stem cells

Liver cancer stem cells (CSCs) have been identified and shown to have self-renewal and differentiation properties; however, the biology of these hepatic CSCs remains largely unknown. Here, we analyzed transcriptome gene expression profiles of liver CSCs and non-CSCs from hepatocellular carcinoma (HC...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Zhu, Pingping, Wang, Yanying, He, Lei, Huang, Guanling, Du, Ying, Zhang, Geng, Yan, Xinlong, Xia, Pengyan, Ye, Buqing, Wang, Shuo, Hao, Lu, Wu, Jiayi, Fan, Zusen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607118/
https://ncbi.nlm.nih.gov/pubmed/26426078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81979
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