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HMGB1 induction of clusterin creates a chemoresistant niche in human prostate tumor cells
Development of chemoresistance, especially to docetaxel (DTX), is the primary barrier to the cure of castration-resistant prostate cancer but its mechanism is obscure. Here, we report a seminal crosstalk between dying and residual live tumor cells during treatment with DTX that can result in outgrow...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606829/ https://ncbi.nlm.nih.gov/pubmed/26469759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15085 |
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