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Therapeutic targeting of myeloid-derived suppressor cells involves a novel mechanism mediated by clusterin
Myeloid-derived suppressor cells (MDSCs) constitute a key checkpoint that impedes tumor immunity against cancer. Chemotherapeutic intervention of MDSCs has gained ground as a strategy for cancer therapy but its mechanism remains obscure.We report here a unique mechanism by which monocytic (M)-MDSCs...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942787/ https://ncbi.nlm.nih.gov/pubmed/27405665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29521 |
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