Inhibitory Effect of the Noncamptothecin Topoisomerase I Inhibitor LMP-400 on Female Mice Models and Human Pheochromocytoma Cells

Metastatic pheochromocytoma continues to be an incurable disease, and treatment with conventional cytotoxic chemotherapy offers limited efficacy. In the present study, we evaluated a novel topoisomerase I inhibitor, LMP-400, as a potential treatment for this devastating disease. We found a high expr...

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Detaylı Bibliyografya
Yayımlandı:Endocrinology
Asıl Yazarlar: Schovanek, Jan, Bullova, Petra, Tayem, Yasin, Giubellino, Alessio, Wesley, Robert, Lendvai, Nikoletta, Nölting, Svenja, Kopacek, Juraj, Frysak, Zdenek, Pommier, Yves, Kummar, Shivaani, Pacak, Karel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606751/
https://ncbi.nlm.nih.gov/pubmed/26267380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1476
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