Aging and Loss of Circulating 17β-Estradiol Alters the Alternative Splicing of ERβ in the Female Rat Brain

Loss of circulating 17β-estradiol (E2) that occurs during menopause can have detrimental effects on cognitive function. The efficacy of hormone replacement therapy declines as women become farther removed from the menopausal transition, yet the molecular mechanisms underlying this age-related switch...

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Bibliografiska uppgifter
I publikationen:Endocrinology
Huvudupphovsmän: Shults, Cody L., Pinceti, Elena, Rao, Yathindar S., Pak, Toni R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2015
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606750/
https://ncbi.nlm.nih.gov/pubmed/26295370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1514
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