Aging and Loss of Circulating 17β-Estradiol Alters the Alternative Splicing of ERβ in the Female Rat Brain

Loss of circulating 17β-estradiol (E2) that occurs during menopause can have detrimental effects on cognitive function. The efficacy of hormone replacement therapy declines as women become farther removed from the menopausal transition, yet the molecular mechanisms underlying this age-related switch...

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Detaylı Bibliyografya
Yayımlandı:Endocrinology
Asıl Yazarlar: Shults, Cody L., Pinceti, Elena, Rao, Yathindar S., Pak, Toni R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606750/
https://ncbi.nlm.nih.gov/pubmed/26295370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1514
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