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Aging and Loss of Circulating 17β-Estradiol Alters the Alternative Splicing of ERβ in the Female Rat Brain

Loss of circulating 17β-estradiol (E2) that occurs during menopause can have detrimental effects on cognitive function. The efficacy of hormone replacement therapy declines as women become farther removed from the menopausal transition, yet the molecular mechanisms underlying this age-related switch...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Shults, Cody L., Pinceti, Elena, Rao, Yathindar S., Pak, Toni R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606750/
https://ncbi.nlm.nih.gov/pubmed/26295370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1514
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