Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle

BACKGROUND: Rho kinase (ROCK) and myosin-light chain kinase (MLCK) are key enzymes in smooth muscle contraction. Previous data have suggested that ROCK contribution to human detrusor contraction is increasing with age. Here, we have analyzed the transcriptional expression of Rho kinase isoforms (ROC...

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Pubblicato in:BMC Urol
Autori principali: Kirschstein, Timo, Sahre, Theresa, Kernig, Karoline, Protzel, Chris, Porath, Katrin, Köhling, Rüdiger, Hakenberg, Oliver W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606542/
https://ncbi.nlm.nih.gov/pubmed/26468005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-015-0098-2
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