Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle

BACKGROUND: Rho kinase (ROCK) and myosin-light chain kinase (MLCK) are key enzymes in smooth muscle contraction. Previous data have suggested that ROCK contribution to human detrusor contraction is increasing with age. Here, we have analyzed the transcriptional expression of Rho kinase isoforms (ROC...

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Detalhes bibliográficos
Publicado no:BMC Urol
Main Authors: Kirschstein, Timo, Sahre, Theresa, Kernig, Karoline, Protzel, Chris, Porath, Katrin, Köhling, Rüdiger, Hakenberg, Oliver W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606542/
https://ncbi.nlm.nih.gov/pubmed/26468005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12894-015-0098-2
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