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Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro

AIM: Activation of muscarinic receptors on the detrusor smooth muscle is followed by contraction, which involves both myosin light chain kinase (MLCK) and Rho kinase (ROCK). The aim of this study was to determine the relative contributions of MLCK and ROCK to carbachol-induced contraction of human d...

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Главные авторы: Kirschstein, Timo, Protzel, Chris, Porath, Katrin, Sellmann, Tina, Köhling, Rüdiger, Hakenberg, Oliver W
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075738/
https://ncbi.nlm.nih.gov/pubmed/24122009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.126
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