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Mammary stem cell self-renewal is regulated by Slit2/Robo1 signaling through Snail and mInscuteable

Tissue homeostasis requires somatic stem cell maintenance; however, mechanisms regulating this process during organogenesis are not well understood. Here, we identify asymmetrically renewing basal and luminal stem cells in the mammary end bud. We demonstrate that SLIT2/ROBO1 signaling regulates the...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Ballard, Mimmi S., Zhu, Anna, Iwai, Naomi, Stensrud, Michael, Mapps, Aurelia, Postiglione, Maria Pia, Knoblich, Juergen A., Hinck, Lindsay
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4606466/
https://ncbi.nlm.nih.gov/pubmed/26440891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.006
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