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Selective Histone Deacetylase 6 inhibition Prolongs Survival in a Lethal Two-hit Model
INTRODUCTION: Hemorrhagic shock (HS) followed by a subsequent insult (“second hit”) often initiates an exaggerated systemic inflammatory response and multiple organ failure. We have previously demonstrated that valproic acid, a pan histone deacetylase (HDAC) inhibitor, could improve survival in a ro...
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| Pubblicato in: | J Surg Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4606460/ https://ncbi.nlm.nih.gov/pubmed/25837686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2015.02.070 |
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