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Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

The entorhinal cortex (EC) plays a central role in episodic memory and is among the earliest sites of neurodegeneration and neurofibrillary tangle formation in Alzheimer's disease. Given its importance in memory and dementia, the ability to selectively modulate gene expression or neuronal funct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain Struct Funct
Hauptverfasser: Yetman, Michael J., Lillehaug, Sveinung, Bjaalie, Jan G., Leergaard, Trygve B., Jankowsky, Joanna L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605847/
https://ncbi.nlm.nih.gov/pubmed/25869275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-015-1040-9
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